Ivermectin B1a-d2

Pricing Availability Delivery Time Qty
Cat.No. 5156 - Ivermectin B1a-d2 | C48H72D2O14
Description: Deuterated ivermectin B1a (Cat. No. 1260)
Chemical Name: 22,23-Dihydroavermectin B1a-d2
Purity: ≥98% (HPLC)

Biological Activity

Deuterated ivermectin B1a (Cat. No. 1260).

Technical Data

M. Wt 877.1
Formula C48H72D2O14
Storage Store at +4°C
Purity ≥98% (HPLC)
PubChem ID 90489016
Smiles O[C@H]1[C@H](C)O[C@](O[C@H]2[C@@H](O[C@](O[C@H](/C(C)=C/C[C@@]4([H])O[C@@]7([C@H]([2H])C([2H])[C@H](C)[C@@]([H])([C@]([H])(C)CC)O7)C[C@@H]6C4)[C@@H](C)/C=C/C=C3/[C@]5(O)[C@]([C@H](O)C(C)=CC5C(O6)=O)([H])OC3)([H])C[C@@H]2OC)C)([H])C[C@@H]1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 43.85 50

Preparing Stock Solutions

The following data is based on the product molecular weight 877.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.14 mL 5.7 mL 11.4 mL
5 mM 0.23 mL 1.14 mL 2.28 mL
10 mM 0.11 mL 0.57 mL 1.14 mL
50 mM 0.02 mL 0.11 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

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Keywords: Ivermectin B1a-d2 B1ad2 deuterated stable isotope isotopically labeled Nicotinic (a7) Receptors

Citations for Ivermectin B1a-d2

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Literature in this Area


Neurodegeneration Product Guide

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Nicotinic ACh Receptors

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.


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Learning & Memory

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Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.


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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

Pathways for Ivermectin B1a-d2


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