Ivermectin B1a-d2

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Cat.No. 5156 - Ivermectin B1a-d2 | C48H72D2O14
Description: Deuterated ivermectin B1a (Cat. No. 1260)
Chemical Name: 22,23-Dihydroavermectin B1a-d2
Purity: ≥98% (HPLC)

Biological Activity

Deuterated version of ivermectin B1a.

Ivermectin also available.

Technical Data

M. Wt 877.1
Formula C48H72D2O14
Storage Store at +4°C
Purity ≥98% (HPLC)
PubChem ID 90489016
Smiles O[C@H]1[C@H](C)O[C@](O[C@H]2[C@@H](O[C@](O[C@H](/C(C)=C/C[C@@]4([H])O[C@@]7([C@H]([2H])C([2H])[C@H](C)[C@@]([H])([C@]([H])(C)CC)O7)C[C@@H]6C4)[C@@H](C)/C=C/C=C3/[C@]5(O)[C@]([C@H](O)C(C)=CC5C(O6)=O)([H])OC3)([H])C[C@@H]2OC)C)([H])C[C@@H]1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 43.85 50

Preparing Stock Solutions

The following data is based on the product molecular weight 877.1. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 2.28 mL 11.4 mL 22.8 mL
2.5 mM 0.46 mL 2.28 mL 4.56 mL
5 mM 0.23 mL 1.14 mL 2.28 mL
25 mM 0.05 mL 0.23 mL 0.46 mL

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References are publications that support the biological activity of the product.

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Citations for Ivermectin B1a-d2

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease

Pain Research Product Guide

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  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
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Nicotinic ACh Receptors

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.


Alzheimer's Poster

Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.

Learning & Memory

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.


Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.