Isamoltane hemifumarate

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Cat.No. 0992 - Isamoltane hemifumarate | C16H22N2O2.½C4H4O4 | CAS No. 874882-92-5
Description: 5-HT1B antagonist
Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)]-propan-2-ol hemifumarate
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for Isamoltane hemifumarate

Isamoltane hemifumarate is a 5-HT1B antagonist, approximately 30-fold selective over 5-HT1A. Also possesses affinity for β-adrenergic receptors.

Technical Data for Isamoltane hemifumarate

M. Wt 332.4
Formula C16H22N2O2.½C4H4O4
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 874882-92-5
PubChem ID 45073435

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Isamoltane hemifumarate

Solvent Max Conc. mg/mL Max Conc. mM
water 3.32 10 with gentle warming

Preparing Stock Solutions for Isamoltane hemifumarate

The following data is based on the product molecular weight 332.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.08 mL 150.42 mL 300.84 mL
0.5 mM 6.02 mL 30.08 mL 60.17 mL
1 mM 3.01 mL 15.04 mL 30.08 mL
5 mM 0.6 mL 3.01 mL 6.02 mL

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Product Datasheets for Isamoltane hemifumarate

Certificate of Analysis / Product Datasheet
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References for Isamoltane hemifumarate

References are publications that support the biological activity of the product.

Waldmeier et al (1988) Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. Naunyn Schmiedebergs Arch.Pharmacol. 337 609 PMID: 2905765

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Citations for Isamoltane hemifumarate

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