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Biological Activity for Irbesartan
Irbesartan is a potent angiotensin II type 1 receptor (AT1) antagonist (IC50 = 1.3 nM). Displays antihypertensive activity. Orally bioavailable.
Technical Data for Irbesartan
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Irbesartan
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Irbesartan
The following data is based on the product molecular weight 428.53. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.33 mL||11.67 mL||23.34 mL|
|5 mM||0.47 mL||2.33 mL||4.67 mL|
|10 mM||0.23 mL||1.17 mL||2.33 mL|
|50 mM||0.05 mL||0.23 mL||0.47 mL|
References for Irbesartan
References are publications that support the biological activity of the product.
Burnier et al (2001) Angiotensin II type 1 receptor blockers. Circulation 103 904 PMID: 11171802
If you know of a relevant reference for Irbesartan, please let us know.
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Citations for Irbesartan
Citations are publications that use Tocris products.
Currently there are no citations for Irbesartan. Do you know of a great paper that uses Irbesartan from Tocris? Please let us know.
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Literature in this Area
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