Selective 5-HT1A receptor agonist (Ki = 10 nM). Anxiolytic in vivo.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 401.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.49 mL||12.45 mL||24.91 mL|
|5 mM||0.5 mL||2.49 mL||4.98 mL|
|10 mM||0.25 mL||1.25 mL||2.49 mL|
|50 mM||0.05 mL||0.25 mL||0.5 mL|
References are publications that support the products' biological activity.
Maj et al (1987) Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions. J.Neural.Transm. 70 1 PMID: 2889795
Traber et al (1984) Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain Res.Bull. 12 741 PMID: 6541079
If you know of a relevant reference for Ipsapirone, please let us know.
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Keywords: Ipsapirone, supplier, Selective, 5-HT1A, agonists, Serotonin, Receptors, TVXQ7821, TVX, Q, 7821, 5-HT1A, Receptors, 5-HT1A, Receptors, Tocris Bioscience
1 Citation for Ipsapirone
Citations are publications that use Tocris products. Selected citations for Ipsapirone include:
Rozeske et al (2011) Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus. J Neurosci 31 14107 PMID: 21976495
Do you know of a great paper that uses Ipsapirone from Tocris? If so please let us know.
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