Immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||1.2||5mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 240.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.16 mL||20.81 mL||41.61 mL|
|5 mM||0.83 mL||4.16 mL||8.32 mL|
|10 mM||0.42 mL||2.08 mL||4.16 mL|
|50 mM||0.08 mL||0.42 mL||0.83 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Schon and Schon (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr.Med.Chem. 14 681 PMID: 17346155
Averett et al (2007) The pharmacology of endosomal TLR agonists in viral disease. Biochem.Soc.Trans. 35 1468 PMID: 18031247
If you know of a relevant reference for Imiquimod, please let us know.
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Keywords: Imiquimod, supplier, Toll-like, receptors, 7, TLR7, agonists, R837, R, 837, Toll-like, Receptors, Antivirals, Toll-like, Receptors, Tocris Bioscience
Citations for Imiquimod
Citations are publications that use Tocris products.
Currently there are no citations for Imiquimod. Do you know of a great paper that uses Imiquimod from Tocris? If so please let us know.