ICI 154,129

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Cat.No. 0827 - ICI 154,129 | N,N-diallyl-Tyr-Gly-ψ-(CH2S)-Phe-Leu-OH | CAS No. 83420-94-4
Description: δ selective peptide antagonist
Datasheet
Citations (1)
Reviews
Literature (5)

Biological Activity

Selective δ opioid antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt 638.83
Formula C34H46N4O6S
Sequence YGFL

(Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH2S))

Storage Desiccate at -20°C
CAS Number 83420-94-4
PubChem ID 3035055
InChI Key CZRZYRKTYLLLRL-DTXPUJKBSA-N
Smiles CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)SCCNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N(CC=C)CC=C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in methanol

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References

References are publications that support the biological activity of the product.

Shaw et al (1982) Selective antagonists at the opiate delta-receptor. Life Sci. 31 1259 PMID: 6128652

Rees and Hunter (1990) Opioid Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 805


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1 Citation for ICI 154,129

Citations are publications that use Tocris products. Selected citations for ICI 154,129 include:

Jiang et al (2015) Analgesic roles of peripheral intrinsic met-enkephalin and dynorphin A in long-lasting inflammatory pain induced by complete Freund's adjuvant in rats. J Pharmacol Exp Ther 9 2344 PMID: 26136984


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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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