Group I mGlu Receptor Tocriset™

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Contents of Tocriset:

Cat.No. Product Name / Activity
1212MPEP hydrochloride
selective mGlu5 antagonist
specific group I mGlu agonist
non-selective group I/group II antagonist
1237LY 367385
selective mGlu1a antagonist
0188L-Quisqualic acid
Potent group I mGlu agonist
Description: Selection of 5 group I mGlu receptor ligands (Cat. Nos. 0805, 0188, 1237, 1212 and 0337)

Biological Activity

Contains the listed products as lyophilised solids which can be used to investigate the pharmacology of Group I mGlu receptors.

Technical Data

Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.

Please see individual product listings for specific technical data and certificate of analysis.

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

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Citations for Group I mGlu Receptor Tocriset™

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Metabotropic Glutamate Receptors

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.