GLP-1 (7-37)

Pricing Availability Delivery Time Qty
Cat.No. 5374 - GLP-1 (7-37) | His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly | CAS No. 106612-94-6
Description: Endogenous bioactive GLP-1 receptor ligand
Datasheet
Citations
Literature

Biological Activity

Endogenous GLP-1 receptor ligand; bioactive and truncated form of GLP-1; insulinotropic hormone.

Technical Data

M. Wt 3355.71
Formula C151H228N40O47
Sequence HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Storage Store at -20°C
CAS Number 106612-94-6
PubChem ID 16133830
InChI Key GCYXWQUSHADNBF-AAEALURTSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 3355.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.3 mL 1.49 mL 2.98 mL
5 mM 0.06 mL 0.3 mL 0.6 mL
10 mM 0.03 mL 0.15 mL 0.3 mL
50 mM 0.01 mL 0.03 mL 0.06 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Marchetti et al (2012) A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia 55 3262 PMID: 22965295

Ban et al (2010) Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 151 1520 PMID: 20172966


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Keywords: Endogenous GLP-1 receptor ligands bioactive truncated form Glucagon like peptide receptor insulinotropic proglucagon agonists Glucagon-Like Peptide 1 Receptors

Citations for GLP-1 (7-37)

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Pathways for GLP-1 (7-37)

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