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Biological Activity for GAMS
Historic kainate/quisqualate selective antagonist; may be able to distinguish between AMPA and kainate receptors. Anticonvulsant.
Technical Data for GAMS
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for GAMS
References for GAMS
References are publications that support the biological activity of the product.
Croucher et al (1984) γ-D-Glutamylaminomethylsulphonic acid (GAMS), a kainate and quisqualate antagonist, prevents sound-induced seizures in DBA/2 mice. Brain Res. 322 111 PMID: 6097331
Wilding and Huettner (1996) Antagonist pharmacology of kainate- and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring receptors. Mol.Pharmacol. 49 540 PMID: 8643094
Zhou et al (1993) γ-D-Glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced response in Xenopus oocytes expressing chick brain glutamate receptors. Neuropharmacology 32 767 PMID: 7692340
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Keywords: GAMS, GAMS supplier, Non-selective, Ionotropic, Glutamate, 0150, Tocris Bioscience
Citations for GAMS
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Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.