Discontinued Product

GAMS (Cat. No. 0150) has been withdrawn from sale for commercial reasons.
Cat.No. 0150 - GAMS | CAS No. 90237-02-8
Description: Non-NMDA antagonist
Chemical Name: g-D-Glutamylaminomethylsulfonic acid

Biological Activity

Historic kainate/quisqualate selective antagonist; may be able to distinguish between AMPA and kainate receptors. Anticonvulsant.

Technical Data

M. Wt 240.23
Storage Store at RT
CAS Number 90237-02-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

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Safety Datasheet


References are publications that support the biological activity of the product.

Croucher et al (1984) γ-D-Glutamylaminomethylsulphonic acid (GAMS), a kainate and quisqualate antagonist, prevents sound-induced seizures in DBA/2 mice. Brain Res. 322 111 PMID: 6097331

Wilding and Huettner (1996) Antagonist pharmacology of kainate- and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring receptors. Mol.Pharmacol. 49 540 PMID: 8643094

Zhou et al (1993) γ-D-Glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced response in Xenopus oocytes expressing chick brain glutamate receptors. Neuropharmacology 32 767 PMID: 7692340

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Keywords: GAMS, GAMS supplier, Non-selective, Ionotropic, Glutamate, 0150, Tocris Bioscience

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