Formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 values are 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization respectively).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 404.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.47 mL||12.36 mL||24.73 mL|
|5 mM||0.49 mL||2.47 mL||4.95 mL|
|10 mM||0.25 mL||1.24 mL||2.47 mL|
|50 mM||0.05 mL||0.25 mL||0.49 mL|
References are publications that support the products' biological activity.
Schepetkin et al (2007) High-throughput screening for small molecule activators of neutrophils: Identification of novel N-formyl peptide receptor agonists. Mol.Pharmacol. 71 1061 PMID: 17229869
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Keywords: FPR A14, supplier, Formyl, peptide, FPR, agonists, FPRA14, receptors, Formyl, Peptide, Receptors, Formyl, Peptide, Receptors, Tocris Bioscience
1 Citation for FPR A14
Citations are publications that use Tocris products. Selected citations for FPR A14 include:
Yan et al (2015) Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. J Hepatol 63 420 PMID: 25828472
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