Discontinued Product

Flurbiprofen (Cat. No. 1769) has been withdrawn from sale for commercial reasons.
Description: Cyclooxygenase inhibitor
Chemical Name: 2-Fluoro-α-methyl-[1,1'-biphenyl]-4-acetic acid
Purity: ≥99% (HPLC)
Literature (2)

Biological Activity for Flurbiprofen

Flurbiprofen is a potent inhibitor of cyclooxygenase (IC50 values are 0.1 and 0.4 μM for inhibition of human COX-1 and COX-2 respectively). Analgesic, anti-inflammatory and antipyretic in vivo. Inhibits tumor cell growth in vitro and in vivo. Regulates prostate stem cell antigen through activation of Akt kinase. Also inhibits fibroblast proliferation in vitro.

Technical Data for Flurbiprofen

M. Wt 244.26
Formula C15H13FO2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 5104-49-4
PubChem ID 3394
Smiles CC(C(O)=O)C1=CC=C(C(F)=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: Flurbiprofen, Flurbiprofen supplier, Cyclooxygenase, inhibitors, inhibits, COX, Oxidase, Oxygenases, Oxidases, stem, cells, Akt, kinases, Analgesics, anti-inflammatory, and, antipyretics, Stem, Cell, Signaling, 1769, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Flurbiprofen, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Flurbiprofen

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Currently there are no citations for Flurbiprofen.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.