You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Discontinued ProductFexofenadine hydrochloride (Cat. No. 2429) has been withdrawn from sale for commercial reasons.
Biological Activity for Fexofenadine hydrochloride
Fexofenadine hydrochloride is a selective histamine H1 receptor antagonist (pKi = 8.1). Active metabolite of Terfenadine (Cat. No. 3948) that displays non-sedating antiallergic effects. Fexofenadine hydrochloride counteracts histamine mediated immune suppression and improves immunotherapy response.
Compound Libraries for Fexofenadine hydrochloride
Technical Data for Fexofenadine hydrochloride
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Fexofenadine hydrochloride
References for Fexofenadine hydrochloride
References are publications that support the biological activity of the product.
Markham and Wagstaff (1998) Fexofenadine. Drugs 55 269 PMID: 9506246
Sakairi et al (2005) Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis. Pharmacology 75 76 PMID: 16037679
Gillard and Chatelaine (2006) Changes in pH differently affect the binding properties of histamine H1 receptor antagonists. Eur.J.Pharmacol. 530 205 PMID: 16388798
Li et al (2022) The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1. Cancer Cell 40 36 PMID: 34822775
View Related Products by Product Action
Keywords: Fexofenadine hydrochloride, Fexofenadine hydrochloride supplier, H1, receptor, antagonists, non-sedating, antiallergic, agent, Receptors, Histamine, histaminergic, MDL16455, MDL, 16455, Terfenidine, 2429, Tocris Bioscience
1 Citation for Fexofenadine hydrochloride
Citations are publications that use Tocris products. Selected citations for Fexofenadine hydrochloride include:
Won et al (2013) A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo " connect". Mucosal Immunol 53 982 PMID: 23878024
Reviews for Fexofenadine hydrochloride
There are currently no reviews for this product. Be the first to review Fexofenadine hydrochloride and earn rewards!
Have you used Fexofenadine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.