You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
High affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM). Exhibits >6-fold selectivity for RIOK2 over a panel of 456 kinases. Inhibits ERG protein and potently inhibits growth of ERG-positive VCaP prostate cancer cells in vitro (IC50 = 169 nM) but not ERG-negative cell lines. Also inhibits growth of VCaP xenografts in mice.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 255.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.92 mL||19.58 mL||39.17 mL|
|5 mM||0.78 mL||3.92 mL||7.83 mL|
|10 mM||0.39 mL||1.96 mL||3.92 mL|
|50 mM||0.08 mL||0.39 mL||0.78 mL|
References are publications that support the biological activity of the product.
Mohamed et al (2018) Identification of a small molecule that selectively inhibits ERG-positive cancer cell growth. Cancer Res. 78 3659 PMID: 29712692
If you know of a relevant reference for ERGi-USU, please let us know.
View Related Products by Product Action
Keywords: ERGi-USU, ERGi-USU supplier, Rio2, kinase, RIOK2, atypical, protein, aPK, ribosome, biogenesis, inhibitors, inhibits, high, affinity, ERG, prostate, cancer, Other, Kinases, 6632, Tocris Bioscience
Citations for ERGi-USU
Citations are publications that use Tocris products.
Currently there are no citations for ERGi-USU. Do you know of a great paper that uses ERGi-USU from Tocris? Please let us know.
Reviews for ERGi-USU
There are currently no reviews for this product. Be the first to review ERGi-USU and earn rewards!
Have you used ERGi-USU?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.