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Cat.No. 3811 - Emodin | C15H10O5 | CAS No. 518-82-1
Description: Naturally occurring anthraquinone; displays anti-inflammatory, antitumor and neuroprotective activity
Chemical Name: 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione
Purity: ≥97% (HPLC)

Biological Activity for Emodin

Emodin is a naturally occurring anthraquinone that displays a range of biological activities. Exhibits anti-inflammatory, antitumor and neuroprotective effects.

Technical Data for Emodin

M. Wt 270.24
Formula C15H10O5
Storage Store at +4°C
Purity ≥97% (HPLC)
CAS Number 518-82-1
PubChem ID 3220
Smiles O=C2C3=C(C=C(C)C=C3O)C(C1=CC(O)=CC(O)=C12)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Emodin

Solvent Max Conc. mg/mL Max Conc. mM
1eq. NaOH 27.02 100
DMSO 13.51 50

Preparing Stock Solutions for Emodin

The following data is based on the product molecular weight 270.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL
10 mM 0.37 mL 1.85 mL 3.7 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

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References for Emodin

References are publications that support the biological activity of the product.

Wu et al (2007) Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium. Life Sci. 81 1332 PMID: 17939930

Chun-Guang et al (2010) Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur.J.Pharmacol. 627 33 PMID: 19857484

Liu et al (2010) Neuroprotective effects of emodin in rat cortical neurons against β-amyloid-induced neurotoxicity. Brain Res. 1347 149 PMID: 20573598

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