EMDT oxalate

Pricing Availability Delivery Time Qty
Cat.No. 4209 - EMDT oxalate | C15H22N2O.C2H2O4 | CAS No. 263744-72-5
Description: Selective 5-HT6 agonist
Chemical Name: 2-Ethyl-5-methoxy-N,N-dimethyl-1H-indole-3-ethanamine oxalate
Purity: ≥98% (HPLC)

Biological Activity

Selective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors). Exhibits potency comparable to serotonin for the activation of adenylate cyclase. Displays antidepressant-like effects.

Technical Data

M. Wt 336.38
Formula C15H22N2O.C2H2O4
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 263744-72-5
PubChem ID 90488919
Smiles CCC2=C(CCN(C)C)C1=CC(OC)=CC=C1N2.O=C(C(O)=O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 33.64 100
water 16.82 50

Preparing Stock Solutions

The following data is based on the product molecular weight 336.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL
10 mM 0.3 mL 1.49 mL 2.97 mL
50 mM 0.06 mL 0.3 mL 0.59 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Glennon et al (2000) 2-Substituted tryptamines: Agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 43 1011 PMID: 10715164

Svenningsson et al (2007) Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation. J.Neurosci. 27 4201 PMID: 17428998

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