Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32 (Cat. No. 6291). Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.
ELA-14 negative control (Cat.No. 6294) also available.
Sold under agreement from the Agency for Science, Technology and Research (A*STAR), ETPL, and affiliates including the Institute of Medical Biology.
(Modifications: X = Glp)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962 PMID: 26986036
If you know of a relevant reference for ELA-14 (human), please let us know.
View Related Products by Product Action
Keywords: ELA-14 (human), ELA-14 (human) supplier, Apelin, receptor, agonist, agonism, APJ, ELABELA, analog, beta-arrestin-2, b-arrestin-2, β-arrestin-2, Gail, Galphail, Gαil, blood, pressure, active, in, vivo, ELA, (19-32), (human), Receptors, 6293, Tocris Bioscience
Citations for ELA-14 (human)
Citations are publications that use Tocris products.
Currently there are no citations for ELA-14 (human). Do you know of a great paper that uses ELA-14 (human) from Tocris? Please let us know.
Reviews for ELA-14 (human)
There are currently no reviews for this product. Be the first to review ELA-14 (human) and earn rewards!
Have you used ELA-14 (human)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.