Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewELA-11 (human)
Discontinued Product
ELA-11 (human) (Cat. No. 6698) has been withdrawn from sale for commercial reasons.
Description: High affinity apelin agonist
Biological Activity for ELA-11 (human)
High affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32 (Cat. No. 6291). Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
Technical Data for ELA-11 (human)
| M. Wt | 1283.57 |
| Formula | C58H90N16O13S2 |
| Sequence | CMPLHSRVPFP |
| Storage | Store at -20°C |
| CAS Number | 1784687-32-6 |
| PubChem ID | 127043376 |
| InChI Key | XXKPNJFJXZBRMX-HDKAIKTRSA-N |
| Smiles | [H]N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for ELA-11 (human)
References for ELA-11 (human)
References are publications that support the biological activity of the product.
Yang et al (2017) Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension. Circulation 135 1160 PMID: 28137936
Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962 PMID: 26986036
View Related Products by Target
View Related Products by Product Action
Keywords: ELA-11 (human), ELA-11 (human) supplier, high, affinity, apelin, APJ, receptor, agonists, agonism, Elabela, fragment, Apelin, Receptors, 6698, Tocris Bioscience
Citations for ELA-11 (human)
Citations are publications that use Tocris products.
Currently there are no citations for ELA-11 (human).
Reviews for ELA-11 (human)
There are currently no reviews for this product. Be the first to review ELA-11 (human) and earn rewards!
Have you used ELA-11 (human)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image