EIT hydrobromide

Pricing Availability Delivery Time Qty
Cat.No. 0873 - EIT hydrobromide | C3H8N2S.HBr | CAS No. 1071-37-0
Description: Selective iNOS inhibitor, acts arginine binding site
Chemical Name: (S)-Ethylisothiourea hydrobromide

Biological Activity

Potent, selective and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).

Technical Data

M. Wt 185.08
Formula C3H8N2S.HBr
Storage Store at RT
CAS Number 1071-37-0
PubChem ID 200213
Smiles NC(SCC)=N.Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 18.51 100

Preparing Stock Solutions

The following data is based on the product molecular weight 185.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.4 mL 27.02 mL 54.03 mL
5 mM 1.08 mL 5.4 mL 10.81 mL
10 mM 0.54 mL 2.7 mL 5.4 mL
50 mM 0.11 mL 0.54 mL 1.08 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Garvey et al (1994) Potent and selective inhibition of human nitric oxide synthase. J.Biol.Chem. 269 26669 PMID: 7523409

Nakane et al (1995) Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol.Pharmacol. 47 831 PMID: 7536889

Squadrito et al (1996) Effects of S-ethylisothiourea, a potent inhibitor of nitirc oxide synthase, alone or in combination with a nitric oxide donor in splanchnic artery occlusion shock. Br.J.Pharmacol. 119 23 PMID: 8872352

If you know of a relevant reference for EIT hydrobromide, please let us know.

View Related Products by Target

View Related Products by Product Action

View all iNOS Inhibitors

Keywords: EIT hydrobromide, supplier, Selective, iNOS, inhibitors, inhibits, arginine, binding, site, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, iNOS, iNOS, Tocris Bioscience

Citations for EIT hydrobromide

Citations are publications that use Tocris products.

Currently there are no citations for EIT hydrobromide. Do you know of a great paper that uses EIT hydrobromide from Tocris? If so please let us know.

Reviews for EIT hydrobromide

There are currently no reviews for this product. Be the first to review EIT hydrobromide and earn rewards!

Have you used EIT hydrobromide?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area


Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling