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Submit Review(E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid
Discontinued Product
(E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid (Cat. No. 0539) has been withdrawn from sale for commercial reasons.
Description: GHB receptor ligand
Chemical Name: trans-4-hydroxy-4-(4-nitrophenyl)crotonic acid
Biological Activity
The most potent of a series of analogues at binding to the γ-hydroxybutyric acid (GHB) receptor and for inhibition of dopamine release (18-fold more potent than GHB).
Technical Data
| M. Wt | 223.19 |
| Storage | Store at RT |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References
References are publications that support the biological activity of the product.
Hechler et al (1993) γ-hydroxybutyrate ligands possess antiDArgic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406 PMID: 8095552
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Keywords: (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid, (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid supplier, Miscellaneous, GABA, GABAB, Receptors, 0539, Tocris Bioscience
Citations for (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid
Citations are publications that use Tocris products.
Currently there are no citations for (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.