(E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid

Discontinued Product

(E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid (Cat. No. 0539) has been withdrawn from sale for commercial reasons.
Cat.No. 0539 - (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid
Description: GHB receptor ligand
Chemical Name: trans-4-hydroxy-4-(4-nitrophenyl)crotonic acid
Datasheet
Citations
Reviews
Literature

Biological Activity

The most potent of a series of analogues at binding to the γ-hydroxybutyric acid (GHB) receptor and for inhibition of dopamine release (18-fold more potent than GHB).

Technical Data

M. Wt 223.19
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Safety Datasheet

References

References are publications that support the biological activity of the product.

Hechler et al (1993) γ-hydroxybutyrate ligands possess antidopaminergic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406 PMID: 8095552

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View all Miscellaneous GABA Ligands

Keywords: (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid, (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid supplier, Miscellaneous, GABA, GABAB, Receptors, 0539, Tocris Bioscience

Citations for (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid

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Currently there are no citations for (E)-4-Hydroxy-4-(4-nitrophenyl)-2-butenoic acid.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.