Dynorphin B

Pricing Availability   Qty
Cat.No. 3196 - Dynorphin B | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr | CAS No. 83335-41-5
Description: Endogenous κ agonist
Citations (1)
Literature (5)

Biological Activity for Dynorphin B

Dynorphin B is an opioid peptide that is the preferred endogenous agonist for the kappa opioid receptor. Displays moderate selectivity for κ1b.

Technical Data for Dynorphin B

M. Wt 1570.85
Formula C74H115N21O17
Storage Desiccate at -20°C
CAS Number 83335-41-5
PubChem ID 25075991
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Dynorphin B

Solubility Soluble to 0.60 mg/ml in water

Product Datasheets for Dynorphin B

Certificate of Analysis / Product Datasheet
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References for Dynorphin B

References are publications that support the biological activity of the product.

Dhawan et al (1996) International union of pharmacology. XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566

Pasternak et al (1999) Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms. Brain Res. 826 289 PMID: 10224306

Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066

If you know of a relevant reference for Dynorphin B, please let us know.

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Keywords: Dynorphin B, Dynorphin B supplier, Endogenous, κ-opioid, kappa-opioid, agonists, KOP, Receptors, OP2, DynorphinB, Kappa, Opioid, 3196, Tocris Bioscience

1 Citation for Dynorphin B

Citations are publications that use Tocris products. Selected citations for Dynorphin B include:

Pedersen et al (2021) A novel luminescence-based-β-arrestin recruitment assay for unmodified receptors. J Biol Chem PMID: 33684444

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