Opioid peptide that is the preferred endogenous agonist for the kappa opioid receptor. Displays moderate selectivity for κ1b.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 0.60 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1570.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.64 mL||3.18 mL||6.37 mL|
|5 mM||0.13 mL||0.64 mL||1.27 mL|
|10 mM||0.06 mL||0.32 mL||0.64 mL|
|50 mM||0.01 mL||0.06 mL||0.13 mL|
References are publications that support the products' biological activity.
Dhawan et al (1996) International union of pharmacology. XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566
Pasternak et al (1999) Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms. Brain Res. 826 289 PMID: 10224306
Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception. Neuropeptides 42 239 PMID: 18440066
If you know of a relevant reference for Dynorphin B, please let us know.
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