Dynorphin B

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Cat.No. 3196 - Dynorphin B | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr | CAS No. 83335-41-5
Description: Endogenous κ agonist
Datasheet
Citations
Reviews
Literature

Biological Activity

Opioid peptide that is the preferred endogenous agonist for the kappa opioid receptor. Displays moderate selectivity for κ1b.

Technical Data

M. Wt 1570.85
Formula C74H115N21O17
Sequence YGGFLRRQFKVVT
Storage Desiccate at -20°C
CAS Number 83335-41-5
PubChem ID 25075991
InChI Key AGTSSZRZBSNTGQ-ITZCFHCWSA-N
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 0.60 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Dhawan et al (1996) International union of pharmacology. XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566

Pasternak et al (1999) Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms. Brain Res. 826 289 PMID: 10224306

Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066


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Citations for Dynorphin B

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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