(±)-CP 47497

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Cat.No. 3500 - (±)-CP 47497 | C21H34O2 | CAS No. 70434-82-1
Description: Potent CB1 agonist
Chemical Name: rel-5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]phenol
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Potent CB1 receptor agonist (Ki = 2.2 nM). Exhibits analgesic, motor depressant, anticonvulsant and hypothermic effects in vivo.

Technical Data

M. Wt 318.49
Formula C21H34O2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 70434-82-1
PubChem ID 90488849
InChI Key OWPXDWMENLSANZ-OPRWNZNUSA-N
Smiles CC(CCCCCC)(C)C(C=C2O)=CC=[C@@]2[C@H]1CCC[C@@H](O)C1.CC(CCCCCC)(C)C(C=C4O)=CC=[C@@]4[C@@H]3CCC[C@H](O)C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.85 100
ethanol 31.85 100

Preparing Stock Solutions

The following data is based on the product molecular weight 318.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.14 mL 15.7 mL 31.4 mL
5 mM 0.63 mL 3.14 mL 6.28 mL
10 mM 0.31 mL 1.57 mL 3.14 mL
50 mM 0.06 mL 0.31 mL 0.63 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Weissman et al (1982) Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol. J.Pharmacol.Exp.Ther. 223 516 PMID: 6290642

Melvin et al (1993) Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol.Pharmacol. 44 1008 PMID: 8246904

Huffman et al (2008) Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg.Med.Chem. 16 322 PMID: 17919913


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Keywords: Potent CB1 agonists cannabinoids Receptors (±)-CP47497 cb1r CB1 Receptors

Citations for (±)-CP 47497

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