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Discontinued Product(±)-CP 47497 (Cat. No. 3500) has been withdrawn from sale for commercial reasons.
Potent CB1 receptor agonist (Ki = 2.2 nM). Exhibits analgesic, motor depressant, anticonvulsant and hypothermic effects in vivo.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Weissman et al (1982) Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol. J.Pharmacol.Exp.Ther. 223 516 PMID: 6290642
Melvin et al (1993) Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol.Pharmacol. 44 1008 PMID: 8246904
Huffman et al (2008) Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg.Med.Chem. 16 322 PMID: 17919913
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Keywords: (±)-CP 47497, (±)-CP 47497 supplier, Potent, CB1, agonists, cannabinoids, Receptors, (±)-CP47497, cb1r, 3500, Tocris Bioscience
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Literature in this Area
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.