Selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Suppresses expression of CD55 and CD46 induced by IL-1β in an inflammatory tumor cell microenvironment; exhibits no effect on basal CD55 or CD46 expression.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 332.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.01 mL||15.04 mL||30.09 mL|
|5 mM||0.6 mL||3.01 mL||6.02 mL|
|10 mM||0.3 mL||1.5 mL||3.01 mL|
|50 mM||0.06 mL||0.3 mL||0.6 mL|
References are publications that support the products' biological activity.
Labrecque et al (2012) Distinct roles for aryl hydrocarbon receptor nuclear translocator and Ah receptor in estrogen-mediated signaling in human cancer cell lines. PLoS ONE 7 e29545 PMID: 22235307
Murray et al (2011) Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Mol.Pharmacol. 79 508 PMID: 21127131
Narayanan et al (2012) Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposure. J.Pharmacol.Exp.Ther. 342 345 PMID: 22553215
If you know of a relevant reference for DiMNF, please let us know.
View Related Products by Product Action
Keywords: DiMNF, supplier, DiMNF, aryl, hydrocarbon, receptors, AhRs, modulators, SAhRMs, anti-inflammatories, anti-inflammatory, Aryl, Hydrocarbon, Receptors, Aryl, Hydrocarbon, Receptors, Tocris Bioscience
Citations for DiMNF
Citations are publications that use Tocris products.
Currently there are no citations for DiMNF. Do you know of a great paper that uses DiMNF from Tocris? If so please let us know.
Reviews for DiMNF
There are currently no reviews for this product. Be the first to review DiMNF and earn rewards!
Have you used DiMNF?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.