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Submit ReviewHapten modified dUTP for non-radioactive labeling of DNA probes for use in in situ hydbridization (ISH). Acts as a substrate for DNA polymerases and is widely used to generate digoxigenin-labeled DNA probes.
M. Wt | 1471.69 |
Formula | C43H65N4O21P3.4C6H15N |
Storage | Store at -20°C |
Purity | ≥95% (HPLC) |
PubChem ID | 101652826 |
InChI Key | FIEZMPZCZUFOFP-UEXZDYCHSA-N |
Smiles | [H][C@]12CC[C@@]3([C@](C[C@H]([C@@]4([C@@H](C5=CC(OC5)=O)CC[C@]34O)C)O)([C@]1(CC[C@H](OCC(NCCCCCC(NC/C=C/C6=CN(C(NC6=O)=O)[C@H]7C[C@@H]([C@H](O7)COP(O)(OP(O)(OP(O)(O)=O)=O)=O)O)=O)=O)C2)C)[H])[H].CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Anderson et al (2005) Incorporation of reporter-labeled nucleotides by DNA polymerases. Biotechniques 38 257 PMID: 15727132
Keywords: Digoxigenin-11-dUTP, Digoxigenin-11-dUTP supplier, ISH, in, situ, hybridization, DNA, probes, random, prime, labeling, labelling, labeled, labelled, PCR, nick, translation, Polymerase, Enzyme, Substrates, /, Activators, Biochemicals, and, Molecular, Biology, 7090, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.