Digoxigenin-11-dUTP

Pricing Availability   Qty
Cat.No. 7090 - Digoxigenin-11-dUTP | C43H65N4O21P3.4C6H15N
Description: Hapten modified dUTP for ISH
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (2)

Biological Activity

Hapten modified dUTP for non-radioactive labeling of DNA probes for use in in situ hydbridization (ISH). Acts as a substrate for DNA polymerases and is widely used to generate digoxigenin-labeled DNA probes.

Technical Data

M. Wt 1471.69
Formula C43H65N4O21P3.4C6H15N
Storage Store at -20°C
Purity ≥95% (HPLC)
PubChem ID 101652826
InChI Key FIEZMPZCZUFOFP-UEXZDYCHSA-N
Smiles [H][C@]12CC[C@@]3([C@](C[C@H]([C@@]4([C@@H](C5=CC(OC5)=O)CC[C@]34O)C)O)([C@]1(CC[C@H](OCC(NCCCCCC(NC/C=C/C6=CN(C(NC6=O)=O)[C@H]7C[C@@H]([C@H](O7)COP(O)(OP(O)(OP(O)(O)=O)=O)=O)O)=O)=O)C2)C)[H])[H].CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble in 10mM Tris-HCl buffer (supplied pre-dissolved - 1mM)

References

References are publications that support the biological activity of the product.

Anderson et al (2005) Incorporation of reporter-labeled nucleotides by DNA polymerases. Biotechniques 38 257 PMID: 15727132


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Keywords: Digoxigenin-11-dUTP, Digoxigenin-11-dUTP supplier, ISH, in, situ, hybridization, DNA, probes, random, prime, labeling, labelling, labeled, labelled, PCR, nick, translation, RNA/DNA, Polymerase, Enzyme, Substrates, /, Activators, Biochemicals, and, Molecular, Biology, 7090, Tocris Bioscience

Citations for Digoxigenin-11-dUTP

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

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Epigenetics

Epigenetics Scientific Review

Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.