Dapoxetine hydrochloride

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Cat.No. 4358 - Dapoxetine hydrochloride | C21H23NO.HCl | CAS No. 129938-20-1
Description: Selective serotonin reuptake inhibitor
Chemical Name: (S)-N,N-Dimethyl-α-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
Purity: ≥99% (HPLC)

Biological Activity

Selective serotonin reuptake inhibitor (SSRI).

Technical Data

M. Wt 341.87
Formula C21H23NO.HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 129938-20-1
PubChem ID 71352
Smiles CN([C@H]([C@]3=CC=CC=C3)CCOC1=CC=CC2=C1C=CC=C2)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 25.64 75
DMSO 34.19 100

Preparing Stock Solutions

The following data is based on the product molecular weight 341.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.93 mL 14.63 mL 29.25 mL
5 mM 0.59 mL 2.93 mL 5.85 mL
10 mM 0.29 mL 1.46 mL 2.93 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

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References are publications that support the biological activity of the product.

Merck Index 14 2818

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Citations for Dapoxetine hydrochloride

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Neurodegeneration Product Guide

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5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.