Dapoxetine hydrochloride

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Cat.No. 4358 - Dapoxetine hydrochloride | C21H23NO.HCl | CAS No. 129938-20-1
Description: Selective serotonin reuptake inhibitor
Chemical Name: (S)-N,N-Dimethyl-α-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
Purity: ≥99% (HPLC)

Biological Activity

Selective serotonin reuptake inhibitor (SSRI).

Technical Data

M. Wt 341.87
Formula C21H23NO.HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 129938-20-1
PubChem ID 71352
Smiles CN([C@H]([C@]3=CC=CC=C3)CCOC1=CC=CC2=C1C=CC=C2)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 34.19 100
ethanol 34.19 100
water 25.64 75

Preparing Stock Solutions

The following data is based on the product molecular weight 341.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.93 mL 14.63 mL 29.25 mL
5 mM 0.59 mL 2.93 mL 5.85 mL
10 mM 0.29 mL 1.46 mL 2.93 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Merck Index 14 2818 PMID:

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Citations for Dapoxetine hydrochloride

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Literature in this Area


Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease
5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Pathways for Dapoxetine hydrochloride


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