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Cat.No. 1417 - Daidzein | C15H10O4 | CAS No. 486-66-8
Description: Arrests cell cycle in G1 phase
Chemical Name: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥99% (HPLC)
Literature (3)

Biological Activity for Daidzein

Daidzein is an analog of the phytoestrogen genistein (Cat. No. 1110). Blocks G1 phase cell cycle progression. Agonist at estrogen receptors.

Technical Data for Daidzein

M. Wt 254.24
Formula C15H10O4
Storage Desiccate at -20°C
Purity ≥99% (HPLC)
CAS Number 486-66-8
PubChem ID 5281708
Smiles OC1=CC=C(C=C1)C1=COC2=CC(O)=CC=C2C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Daidzein

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 25.42 100

Preparing Stock Solutions for Daidzein

The following data is based on the product molecular weight 254.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.93 mL 19.67 mL 39.33 mL
5 mM 0.79 mL 3.93 mL 7.87 mL
10 mM 0.39 mL 1.97 mL 3.93 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

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Product Datasheets for Daidzein

Certificate of Analysis / Product Datasheet
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References for Daidzein

References are publications that support the biological activity of the product.

Casanova et al (1999) Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β in vitro. Toxicol.Sci. 51 236 PMID: 10543025

Higashi and Ogawara (1994) Daidzein inhibits Ins- or Ins-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim.Biophys.Acta 1221 29 PMID: 8130274

Jing et al (1993) Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res. 13 1049 PMID: 8352524

If you know of a relevant reference for Daidzein, please let us know.

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Citations for Daidzein

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