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Discontinued ProductD-(+)-threo-3-Hydroxyaspartic acid (Cat. No. 0182) has been withdrawn from sale for commercial reasons.
Biological Activity for D-(+)-threo-3-Hydroxyaspartic acid
Potent, competitive, transportable inhibitor of L-glutamate and L-aspartate uptake. Less active than (L)-isomer (Cat. No. 0183).
Technical Data for D-(+)-threo-3-Hydroxyaspartic acid
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for D-(+)-threo-3-Hydroxyaspartic acid
References for D-(+)-threo-3-Hydroxyaspartic acid
References are publications that support the biological activity of the product.
Johnston et al (1980) Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate. J.Neurochem. 34 241 PMID: 7452241
McBean and Roberts (1985) Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J.Neurochem. 44 247 PMID: 2856883
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Keywords: D-(+)-threo-3-Hydroxyaspartic acid, D-(+)-threo-3-Hydroxyaspartic acid supplier, Glutamate, Transporters, 0182, Tocris Bioscience
Citations for D-(+)-threo-3-Hydroxyaspartic acid
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Currently there are no citations for D-(+)-threo-3-Hydroxyaspartic acid.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Huntington's Disease Poster
Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.