Potent sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 = 45 nM). Displays no activity at other S1P receptor subtypes (S1P1-3 and S1P5) at concentrations up to 25 μM.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 350.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.85 mL||14.26 mL||28.52 mL|
|5 mM||0.57 mL||2.85 mL||5.7 mL|
|10 mM||0.29 mL||1.43 mL||2.85 mL|
|50 mM||0.06 mL||0.29 mL||0.57 mL|
References are publications that support the biological activity of the product.
Guerrero et al (2011) Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists. Bioorg.Med.Chem.Lett. 22 537 PMID: 22119461
If you know of a relevant reference for CYM 50260, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: CYM 50260, CYM 50260 supplier, CYM50260, sphingosine-1-phosphate, receptors, S1P4, agonists, potent, selective, Sphingosine-1-phosphate, Receptors, 4677, Tocris Bioscience
Citations for CYM 50260
Citations are publications that use Tocris products.
Currently there are no citations for CYM 50260. Do you know of a great paper that uses CYM 50260 from Tocris? Please let us know.
Reviews for CYM 50260
There are currently no reviews for this product. Be the first to review CYM 50260 and earn rewards!
Have you used CYM 50260?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.