Cyanine 7, SE

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Cat.No. 5437 - Cyanine 7, SE | C39H45N3O10S2 | CAS No. 477908-53-5
Description: Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester
Chemical Name: 2-[7-[1-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, inner salt
Purity: ≥95% (HPLC)
Protocols (1)
Literature (1)

Biological Activity

Near-infrared fluorescent dye for labeling of amines. Emission maximum ~764 nm.

Optical Data for Cyanine 7, SE

Cyanine 7, SE Dye Spectra
Emission Color Near-IR
λabs 750 nm
λem 764 nm
Extinction Coefficient (ε) 199000 M-1cm-1
Quantum Yield (φ) 0.3
Reactive Group NHS ester
Reactivity Primary amines
Cell Permeable No
Correction Factor 260 0.022
Correction Factor 280 0.029
Alternative For DyLight 780, Alexa Fluor 750

Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

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Technical Data

M. Wt 779.92
Formula C39H45N3O10S2
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 477908-53-5
PubChem ID 91810959
Smiles CC1(C)C2=C(C=CC(S(=O)(O)=O)=C2)N(CCCCCC(ON3C(CCC3=O)=O)=O)/C1=C/C=C/C=C/C=C/C4=[N+](CC)C5=C(C=C(S(=O)([O-])=O)C=C5)C4(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 77.99 100
DMF 77.99 100

Preparing Stock Solutions

The following data is based on the product molecular weight 779.92. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.28 mL 6.41 mL 12.82 mL
5 mM 0.26 mL 1.28 mL 2.56 mL
10 mM 0.13 mL 0.64 mL 1.28 mL
50 mM 0.03 mL 0.13 mL 0.26 mL

Molarity Calculator

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References are publications that support the biological activity of the product.

Chen et al (2012) Synthesis and biological evaluation of low molecular weight fluorescent imaging agents for the prostate-specific membrane antigen. Bioconjug.Chem. 23 2377 PMID: 23157641

If you know of a relevant reference for Cyanine 7, SE, please let us know.

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Keywords: Cyanine 7, SE, Cyanine 7, SE supplier, Cy7, labeling, amines, fluorescent, imaging, dyes, NHS, ester, Cyanine, Dyes, (Cy, Dyes), Flow, Cytometry, 5437, Tocris Bioscience

Citations for Cyanine 7, SE

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Protocols for Cyanine 7, SE

The following protocol features additional information for the use of Cyanine 7, SE (Cat. No. 5437).

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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