You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Conessine
Potent and selective histamine H3 receptor antagonist (pKi values are 7.61 and 8.27 at rat and human H3 receptors respectively). A steroidal alkaloid that displays in vitro antiplasmodial activity (IC50 = 1.04 μM). Also has high affinity for α2C adrenoceptors (pKi = 7.98).
Technical Data for Conessine
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Conessine
References are publications that support the biological activity of the product.
Zirihi et al (2005) Isolation, characterization and antiplasmodial activity of steroidal alkaloids from Funtumia elastica (Preuss) Stapf. Bioorg.Med.Chem.Lett. 15 2637 PMID: 15863333
Zhao et al (2008) The alkaloid conessine and analogues as potent histamine H3 receptor antagonists. J.Med.Chem. 51 5423 PMID: 18683917
Witte et al (2005) Discovery of a novel natural product of unique chemical structure as a potent and selective histamine H3 receptor (H3R) antagonist. Soc.Neurosci.Abstr. 491 19
View Related Products by Product Action
Keywords: Conessine, Conessine supplier, Potent, selective, H3, receptor, antagonists, Receptors, Histamine, histaminergic, 2409, Tocris Bioscience
Citations for Conessine
Citations are publications that use Tocris products.
Currently there are no citations for Conessine.
Reviews for Conessine
There are currently no reviews for this product. Be the first to review Conessine and earn rewards!
Have you used Conessine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.