Compstatin control peptide

Pricing Availability Delivery Time Qty
Cat.No. 3796 - Compstatin control peptide | Ile-Ala-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Ala-Thr-NH2 | CAS No. 301544-78-5
Description: Control peptide for Compstatin (Cat. No. 2585)
Datasheet
Citations
Literature

Biological Activity

Control peptide for Compstatin (Cat. No. 2585), a complement inhibitor.

Technical Data

M. Wt 1488.67
Formula C66H101N23O17
Sequence IAVVQDWGHHRAT

(Modifications: Thr-13 = C-terminal amide)

Storage Store at -20°C
CAS Number 301544-78-5
PubChem ID 90488879
InChI Key SAJZITDYWAOPDD-LSPMIEDISA-N
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1488.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.67 mL 3.36 mL 6.72 mL
5 mM 0.13 mL 0.67 mL 1.34 mL
10 mM 0.07 mL 0.34 mL 0.67 mL
50 mM 0.01 mL 0.07 mL 0.13 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Sahu et al (1996) Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J.Immunol. 157 884 PMID: 8752942

Fiane et al (1999) Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Xenotransplantation 6 52 PMID: 10355733

Mollnes et al (2002) Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100 1869 PMID: 12176911


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Literature in this Area

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