Compstatin control peptide

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Description: Control peptide for Compstatin (Cat. No. 2585)
Purity: ≥95% (HPLC)
Datasheet
Citations (1)
Reviews

Biological Activity for Compstatin control peptide

Compstatin control peptide is a control peptide for Compstatin, a complement inhibitor.

Active Analog also available.

Technical Data for Compstatin control peptide

M. Wt 1488.67
Formula C66H101N23O17
Sequence IAVVQDWGHHRAT

(Modifications: Thr-13 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 301544-78-5
PubChem ID 90488879
InChI Key SAJZITDYWAOPDD-LSPMIEDISA-N
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Compstatin control peptide

Solubility Soluble to 1 mg/ml in water

Product Datasheets for Compstatin control peptide

Certificate of Analysis / Product Datasheet
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References for Compstatin control peptide

References are publications that support the biological activity of the product.

Sahu et al (1996) Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J.Immunol. 157 884 PMID: 8752942

Fiane et al (1999) Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Xenotransplantation 6 52 PMID: 10355733

Mollnes et al (2002) Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood 100 1869 PMID: 12176911


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Keywords: Compstatin control peptide, Compstatin control peptide supplier, C3-binding, protein, inhibits, inhibitors, complement, activation, Convertase, control, peptide, Complement, 3796, Tocris Bioscience

1 Citation for Compstatin control peptide

Citations are publications that use Tocris products. Selected citations for Compstatin control peptide include:

Yumi et al (2023) Complement dependent TNFα production in neutrophil-like HL60 cells. Biochem Biophys Rep 34 101465 PMID: 37125077


Do you know of a great paper that uses Compstatin control peptide from Tocris? Please let us know.

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