Coenzyme Q10

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Cat.No. 3003 - Coenzyme Q10 | C59H90O4 | CAS No. 303-98-0
Description: Antioxidant
Chemical Name: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

Component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Displays neuroprotective activity.

Technical Data

M. Wt 863.34
Formula C59H90O4
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 303-98-0
PubChem ID 5281915
InChI Key ACTIUHUUMQJHFO-UPTCCGCDSA-N
Smiles O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C(C)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 4.32 5mM with gentle warming
chloroform 43.17 50

Preparing Stock Solutions

The following data is based on the product molecular weight 863.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.16 mL 5.79 mL 11.58 mL
5 mM 0.23 mL 1.16 mL 2.32 mL
10 mM 0.12 mL 0.58 mL 1.16 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Shults (2003) Coenzyme Q10 in neurodegenerative diseases. Curr.Med.Chem. 10 1917 PMID: 12871093

Young et al (2007) Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 12 62 PMID: 17192765


If you know of a relevant reference for Coenzyme Q10, please let us know.

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Keywords: Antioxidant CoenzymeQ10 Antioxidants

1 Citation for Coenzyme Q10

Citations are publications that use Tocris products. Selected citations for Coenzyme Q10 include:

Martin et al (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol 7 101 PMID: 23653115


Do you know of a great paper that uses Coenzyme Q10 from Tocris? If so please let us know.

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Reviews

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for Coenzyme Q10

Protocols

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