cis MZ 1
Negative Control for MZ1 (Cat.No. 6154). Exhibits no significant VHL binding affinity.
Sold under licence from the University of Dundee
External Portal Information
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of MZ 1 is reviewed on the chemical probes website.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 1002.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1 mL||4.99 mL||9.97 mL|
|5 mM||0.2 mL||1 mL||1.99 mL|
|10 mM||0.1 mL||0.5 mL||1 mL|
|50 mM||0.02 mL||0.1 mL||0.2 mL|
References are publications that support the products' biological activity.
Zengerle et al (2015) Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS.Chem.Biol. 10 1770 PMID: 26035625
If you know of a relevant reference for cis MZ 1, please let us know.
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Keywords: cis MZ 1, supplier, cis, MZ1, MZ1, PROTAC, Proteolysis, targeted, chimeras, Bromodomain, BRD2, BRD3, BRD4, BET, proteins, JQ1, VHL, E3, ubiquitin, ligase, HIF-alpha, HIF-a, HIF-α, Ubiquitin, E3, Ligases, Hypoxia, Inducible, Factors, Bromodomains, HIF, PROTACs, Ubiquitin, E3, Ligases, Tocris Bioscience
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