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Biological Activity for CID 2011756
CID 2011756 is a protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50 = 10 μM for PKD1 inhibition). ATP-competitive.
Technical Data for CID 2011756
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CID 2011756
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CID 2011756
The following data is based on the product molecular weight 396.87. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.04 mL||25.2 mL||50.39 mL|
|2.5 mM||1.01 mL||5.04 mL||10.08 mL|
|5 mM||0.5 mL||2.52 mL||5.04 mL|
|25 mM||0.1 mL||0.5 mL||1.01 mL|
References for CID 2011756
References are publications that support the biological activity of the product.
Sharlow et al (2011) Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One 6 e25134 PMID: 21998636
If you know of a relevant reference for CID 2011756, please let us know.
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Citations for CID 2011756
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Literature in this Area
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