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Protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50 = 10 μM for PKD1 inhibition). ATP-competitive.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 396.87. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.04 mL||25.2 mL||50.39 mL|
|2.5 mM||1.01 mL||5.04 mL||10.08 mL|
|5 mM||0.5 mL||2.52 mL||5.04 mL|
|25 mM||0.1 mL||0.5 mL||1.01 mL|
References are publications that support the biological activity of the product.
Sharlow et al (2011) Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One 6 e25134 PMID: 21998636
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