CGP 13501

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Cat.No. 1514 - CGP 13501 | C19H30O2 | CAS No. 56189-68-5
Description: Positive allosteric modulator of GABAB
Chemical Name: 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type.

Technical Data

M. Wt 290.44
Formula C19H30O2
Storage Desiccate at +4°C
Purity ≥98% (HPLC)
CAS Number 56189-68-5
PubChem ID 3519541
InChI Key XGWATTXMMMANFJ-UHFFFAOYSA-N
Smiles CC(C)(C)C1=CC(CC(C)(C)C=O)=CC(=C1O)C(C)(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 29.04 100
DMSO 29.04 100

Preparing Stock Solutions

The following data is based on the product molecular weight 290.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.44 mL 17.22 mL 34.43 mL
5 mM 0.69 mL 3.44 mL 6.89 mL
10 mM 0.34 mL 1.72 mL 3.44 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

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References

References are publications that support the biological activity of the product.

Urwyler et al (2001) Positive allosteric modulation of native and recombinant γ-aminobutyric acidB receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol.Pharmacol. 60 963 PMID: 11641424


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