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CCG 63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Selective amongst RGS proteins, with greatest potency at RGS4. Inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo. Retains activity under reducing conditions.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Blazer et al (2010) Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol.Pharmacol. 78 524 PMID: 20571077
Keywords: CCG 63802, CCG 63802 supplier, CCG63802, inhibitors, inhibits, regulator, g-protein, signaling, signalling, RGS, RGS4, G, proteins, Heterotrimeric, G-protein, GTPases, 4028, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for CCG 63802 include:
Taccola et al (2016) A new model of nerve injury in the rat reveals a role of Regulator of G protein Signaling 4 in tactile hypersensitivity. Experimental Neurology 286 1 PMID: 27641322
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