CCG 2046

Pricing Availability Delivery Time Qty
Cat.No. 2974 - CCG 2046 | C11H10N4 | CAS No. 13017-69-1
Description: Inhibitor of regulator of G-protein signaling 4 (RGS4)
Chemical Name: 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

Inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-Gαo protein-protein interaction signal.

Technical Data

M. Wt 198.22
Formula C11H10N4
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 13017-69-1
PubChem ID 263681
InChI Key OUAQSPOCQDQFEV-UHFFFAOYSA-N
Smiles CC1(CCC)C(C#N)(C#N)C(C#N)1C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 19.82 100
ethanol 0.99 5

Preparing Stock Solutions

The following data is based on the product molecular weight 198.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.04 mL 25.22 mL 50.45 mL
5 mM 1.01 mL 5.04 mL 10.09 mL
10 mM 0.5 mL 2.52 mL 5.04 mL
50 mM 0.1 mL 0.5 mL 1.01 mL

Molarity Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Roman et al (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol.Pharmacol. 71 169 PMID: 17012620


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Keywords: CCG 2046, supplier, inhibitors, inhibits, regulator, G-protein, signaling, 4, RGS4, Gao, Heterotrimeric, CCG2046, G, Protein, (Heterotrimeric), G, Protein, (Heterotrimeric), Tocris Bioscience

1 Citation for CCG 2046

Citations are publications that use Tocris products. Selected citations for CCG 2046 include:

Leister et al (2011) Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells. Curr Chem Genomics 5 21 PMID: 21643507


Do you know of a great paper that uses CCG 2046 from Tocris? If so please let us know.

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