Inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-Gαo protein-protein interaction signal.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 198.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.04 mL||25.22 mL||50.45 mL|
|5 mM||1.01 mL||5.04 mL||10.09 mL|
|10 mM||0.5 mL||2.52 mL||5.04 mL|
|50 mM||0.1 mL||0.5 mL||1.01 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Roman et al (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol.Pharmacol. 71 169 PMID: 17012620
If you know of a relevant reference for CCG 2046, please let us know.
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Keywords: inhibitors inhibits regulator G-protein signaling 4 RGS4 Gao Heterotrimeric CCG2046 G Protein (Heterotrimeric)
1 Citation for CCG 2046
Citations are publications that use Tocris products. Selected citations for CCG 2046 include:
Leister et al (2011) Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells. Curr Chem Genomics 5 21 PMID: 21643507
Do you know of a great paper that uses CCG 2046 from Tocris? If so please let us know.