CCG 2046

Pricing Availability   Qty
Cat.No. 2974 - CCG 2046 | C11H10N4 | CAS No. 13017-69-1
Description: Inhibitor of regulator of G-protein signaling 4 (RGS4)
Chemical Name: 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile
Purity: ≥99% (HPLC)
Citations (1)
Literature (2)

Biological Activity for CCG 2046

CCG 2046 is a inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-Gαo protein-protein interaction signal.

Technical Data for CCG 2046

M. Wt 198.22
Formula C11H10N4
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 13017-69-1
PubChem ID 263681
Smiles CC1(CCC)C(C#N)(C#N)C(C#N)1C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CCG 2046

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 19.82 100

Preparing Stock Solutions for CCG 2046

The following data is based on the product molecular weight 198.22. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.04 mL 25.22 mL 50.45 mL
5 mM 1.01 mL 5.04 mL 10.09 mL
10 mM 0.5 mL 2.52 mL 5.04 mL
50 mM 0.1 mL 0.5 mL 1.01 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

References for CCG 2046

References are publications that support the biological activity of the product.

Roman et al (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol.Pharmacol. 71 169 PMID: 17012620

If you know of a relevant reference for CCG 2046, please let us know.

View Related Products by Product Action

View all Heterotrimeric G-protein GTPase Inhibitors

Keywords: CCG 2046, CCG 2046 supplier, inhibitors, inhibits, regulator, G-protein, signaling, 4, RGS4, Gao, Heterotrimeric, CCG2046, GTPases, 2974, Tocris Bioscience

1 Citation for CCG 2046

Citations are publications that use Tocris products. Selected citations for CCG 2046 include:

Leister et al (2011) Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells. Curr Chem Genomics 5 21 PMID: 21643507

Do you know of a great paper that uses CCG 2046 from Tocris? Please let us know.

Reviews for CCG 2046

There are currently no reviews for this product. Be the first to review CCG 2046 and earn rewards!

Have you used CCG 2046?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis

Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling