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Inhibitor of regulator of G-protein signaling 4 (RGS4). Reduces the RGS4-Gαo protein-protein interaction signal.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 198.22. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.04 mL||25.22 mL||50.45 mL|
|5 mM||1.01 mL||5.04 mL||10.09 mL|
|10 mM||0.5 mL||2.52 mL||5.04 mL|
|50 mM||0.1 mL||0.5 mL||1.01 mL|
References are publications that support the biological activity of the product.
Roman et al (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol.Pharmacol. 71 169 PMID: 17012620
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Keywords: CCG 2046, CCG 2046 supplier, inhibitors, inhibits, regulator, G-protein, signaling, 4, RGS4, Gao, Heterotrimeric, CCG2046, GTPases, 2974, Tocris Bioscience
1 Citation for CCG 2046
Citations are publications that use Tocris products. Selected citations for CCG 2046 include:
Leister et al (2011) Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells. Curr Chem Genomics 5 21 PMID: 21643507
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