Carbetapentane citrate

Pricing Availability Delivery Time Qty
Cat.No. 0454 - Carbetapentane citrate | C20H31NO3.C6H8O7 | CAS No. 23142-01-0
Description: High affinity σ1 ligand
Alternative Names: Pentoxyverine citrate
Chemical Name: 1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

A selective ligand for the σ1 -site.

Technical Data

M. Wt 525.59
Formula C20H31NO3.C6H8O7
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 23142-01-0
PubChem ID 90010
InChI Key AKJDEXBCRLOVTH-UHFFFAOYSA-N
Smiles OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C1(CCCC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.42 75

Preparing Stock Solutions

The following data is based on the product molecular weight 525.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL
10 mM 0.19 mL 0.95 mL 1.9 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Quirion et al (1992) A proposal for the classification of sigma binding sites. TiPS 13 85 PMID: 1315463

Rothman et al (1991) Labelling by [3H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by σ ligands. Mol.Pharmacol. 39 222 PMID: 1847495


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View all σ1 Receptor Ligands

Keywords: High affinity σ1 sigma1 ligand Receptors σ sigma selective Pentoxyverine citrate Sigma1 Receptors

1 Citation for Carbetapentane citrate

Citations are publications that use Tocris products. Selected citations for Carbetapentane citrate include:

Shin et al (2006) Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab 26 1018 PMID: 16340958


Do you know of a great paper that uses Carbetapentane citrate from Tocris? If so please let us know.

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