You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM). Also displays reversible, competitive inhibition of leukotriene A4 (LTA4) hydrolase. Identified as targeting human host proteins that interact with SARS-CoV-2.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 217.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.6 mL||23.01 mL||46.02 mL|
|5 mM||0.92 mL||4.6 mL||9.2 mL|
|10 mM||0.46 mL||2.3 mL||4.6 mL|
|50 mM||0.09 mL||0.46 mL||0.92 mL|
References are publications that support the biological activity of the product.
Zhang et al (1996) Effects of early capt. treatment and its removal on plasma angiotensin converting enzyme (ACE) activity and arginine vasopressin in hypertensive rats (SHR) and normotensive rats (WKY). Clin.Exp.Hypertens. 18 201 PMID: 8869001
Orning et al (1991) Inhibition of leukotriene A4 hydrolase/aminopeptidase by capt. J.Biol.Chem. 266 16507 PMID: 1885582
Fujita and Yoshikawa (1999) LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein. Immunopharmacology. 44 123 PMID: 10604535
Gordon et al A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing. Nature 583 PMID: 32353859
If you know of a relevant reference for Captopril, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Captopril, Captopril supplier, ACE, inhibitors, angiotensin-converting, enzyme, antihypertensives, LTA4, reversible, inhibits, peptidyl, dipeptidase, A, carboxycathepsin, COVID-19, SARS-CoV-2, severe, acute, respiratory, syndrome, Angiotensin-Converting, Enzyme, Aminopeptidases, Hydrolase, 4455, Tocris Bioscience
1 Citation for Captopril
Citations are publications that use Tocris products. Selected citations for Captopril include:
Gupta et al (2014) Opioid receptor function is regulated by post-endocytic peptide processing. J Biol Chem 289 19613 PMID: 24847082
Do you know of a great paper that uses Captopril from Tocris? Please let us know.
Reviews for Captopril
There are currently no reviews for this product. Be the first to review Captopril and earn rewards!
Have you used Captopril?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.