CACA

Discontinued Product

Unfortunately CACA (Cat. No. 0179) has been withdrawn from sale for commercial reasons.
Cat.No. 0179 - CACA | CAS No. 55199-25-2
Description: Partial GABAC agonist
Alternative Names: (Z)-4-Amino-2-butenoic acid
Chemical Name: cis-4-Aminocrotonic acid
Datasheet
Citations
Reviews
Literature

Biological Activity

Partial agonist at GABAC receptors.

Technical Data

M. Wt 101.1
Storage Desiccate at -20°C
CAS Number 55199-25-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 101.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 9.89 mL 49.46 mL 98.91 mL
5 mM 1.98 mL 9.89 mL 19.78 mL
10 mM 0.99 mL 4.95 mL 9.89 mL
50 mM 0.2 mL 0.99 mL 1.98 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet

References

References are publications that support the products' biological activity.

Chebib and Johnston (1997) Stimulation of [3H]GABA and β-[3H]alanine release from rat brain slices by cis-4-aminocrotonic acid. J.Neurochem. 68 786 PMID: 9003070

Drew et al (1984) Bicuculline insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes. Neurosci.Lett. 52 317 PMID: 6097844

Johnston et al (1975) cis and trans-4-Aminocrotonic acid as GABA analogues of restricted conformation. J.Neurochem. 24 157 PMID: 234147

Johnston (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319 PMID: 8885697

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Keywords: CACA, supplier, (Z)-4-Amino-2-butenoic, acid, GABAA-rho, Receptors, GABAA-rho, Receptors, Tocris Bioscience

Citations for CACA

Citations are publications that use Tocris products.

Currently there are no citations for CACA.

Reviews for CACA

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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