Discontinued ProductUnfortunately CACA (Cat. No. 0179) has been withdrawn from sale for commercial reasons.
Partial agonist at GABAC receptors.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 101.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||9.89 mL||49.46 mL||98.91 mL|
|5 mM||1.98 mL||9.89 mL||19.78 mL|
|10 mM||0.99 mL||4.95 mL||9.89 mL|
|50 mM||0.2 mL||0.99 mL||1.98 mL|
References are publications that support the products' biological activity.
Chebib and Johnston (1997) Stimulation of [3H]GABA and β-[3H]alanine release from rat brain slices by cis-4-aminocrotonic acid. J.Neurochem. 68 786 PMID: 9003070
Drew et al (1984) Bicuculline insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes. Neurosci.Lett. 52 317 PMID: 6097844
Johnston et al (1975) cis and trans-4-Aminocrotonic acid as GABA analogues of restricted conformation. J.Neurochem. 24 157 PMID: 234147
Johnston (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319 PMID: 8885697
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Keywords: CACA, supplier, (Z)-4-Amino-2-butenoic, acid, GABAA-rho, Receptors, GABAA-rho, Receptors, Tocris Bioscience
Citations for CACA
Citations are publications that use Tocris products.
Currently there are no citations for CACA.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.