Discontinued Product

CACA (Cat. No. 0179) has been withdrawn from sale for commercial reasons.
Description: Partial GABAC agonist
Alternative Names: (Z)-4-Amino-2-butenoic acid
Chemical Name: cis-4-Aminocrotonic acid
Literature (1)

Biological Activity for CACA

Partial agonist at GABAC receptors.

Technical Data for CACA

M. Wt 101.1
Storage Desiccate at -20°C
CAS Number 55199-25-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for CACA

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for CACA

References are publications that support the biological activity of the product.

Chebib and Johnston (1997) Stimulation of [3H]GABA and β-[3H]alanine release from rat brain slices by cis-4-aminocrotonic acid. J.Neurochem. 68 786 PMID: 9003070

Drew et al (1984) Bicuculline insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes. Neurosci.Lett. 52 317 PMID: 6097844

Johnston et al (1975) cis and trans-4-Aminocrotonic acid as GABA analogues of restricted conformation. J.Neurochem. 24 157 PMID: 234147

Johnston (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319 PMID: 8885697

View Related Products by Target

View Related Products by Product Action

View all GABAA-ρ Receptor Agonists

Keywords: CACA, CACA supplier, (Z)-4-Amino-2-butenoic, acid, GABAA-rho, Receptors, 0179, Tocris Bioscience

Citations for CACA

Citations are publications that use Tocris products.

Currently there are no citations for CACA.

Reviews for CACA

There are currently no reviews for this product. Be the first to review CACA and earn rewards!

Have you used CACA?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.