BzF

Pricing Availability   Qty
Cat.No. 6786 - BzF | C16H15NO3 | CAS No. 104504-45-2
Description: Photoreactive unnatural amino acid; photo-crosslinker
Chemical Name: 4-Benzoyl-L-phenylalanine
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)

Biological Activity

Photoreactive unnatural amino acid. Acts as photo cross-linking probe when incorporated into proteins, including ion channels, transporters and GPCRs. When exposed to UV light it forms a covalent cross-link with a C-H bond-containing group, enabling selective and potent UV-driven photoinactivation of protein function. Has been used to study protein-protein and protein-ligand interactions.

Technical Data

M. Wt 269.3
Formula C16H15NO3
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 104504-45-2
PubChem ID 7020128
InChI Key TVIDEEHSOPHZBR-AWEZNQCLSA-N
Smiles N[C@H](C(O)=O)CC1=CC=C(C(C2=CC=CC=C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
80% acetic acid 13.46 50

Preparing Stock Solutions

The following data is based on the product molecular weight 269.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 7.43 mL 37.13 mL 74.27 mL
2.5 mM 1.49 mL 7.43 mL 14.85 mL
5 mM 0.74 mL 3.71 mL 7.43 mL
25 mM 0.15 mL 0.74 mL 1.49 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Ye et al (2008) Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J.Biol.Chem. 283 1525 PMID: 17993461

Klippenstein et al (2018) Probing ion channel structure and function using light-sensitive amino acids. Trends Biochem.Sci. 43 436 PMID: 29650383

Klippenstein et al (2014) Photoinactivation of glutamate receptors by genetically encoded unnatural amino acids. J.Neurosci. 34 980 PMID: 24431456


If you know of a relevant reference for BzF, please let us know.

Keywords: BzF, BzF supplier, photoreactive, unnatural, amino, acid, UAA, photoactivates, covalent, cross-linking, probe, protein-protein, interaction, Biochemicals, and, Molecular, Biology, Unnatural, Amino, Acids, Photoactivatable, probes, 6786, Tocris Bioscience

Citations for BzF

Citations are publications that use Tocris products.

Currently there are no citations for BzF. Do you know of a great paper that uses BzF from Tocris? Please let us know.

Reviews for BzF

There are currently no reviews for this product. Be the first to review BzF and earn rewards!

Have you used BzF?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide [Spring/Summer 2019]

Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Chemogenetics
  • Epigenetics
  • Fluorescent Imaging
  • PROTACs
  • Signal Transduction
  • Stem Cells