Photoactivatable Cross-linking Probes

Photoactivatable Cross-Linking Probes are unnatural amino acids which are incorporated into proteins, and on exposure to light of a specific wavelength form covalent crosslinks. Triggering of this reaction by light enables precise temporal control and allows for the selective and potent inactivation of protein function. Photoreactive UAAs can be used to investigate the function of proteins, such as ion channels, transporters and GPCRs.

Cat. No. Product Name / Activity
5113 AbK
Photo-crosslinking probe; unnatural amino acid
3312 BzATP triethylammonium salt
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist