BSI 201

Discontinued Product

BSI 201 (Cat. No. 5817) has been withdrawn from sale for commercial reasons.
Description: PARP-1 inhibitor
Alternative Names: Iniparib
Chemical Name: 4-Iodo-3-nitrobenzamide
Purity: ≥98% (HPLC)
Literature (2)

Biological Activity for BSI 201

BSI 201 is a PARP1 inhibitor. Inhibits growth of certain breast cancer cell lines in vitro. Non-selectively modifies cysteine-containing proteins in tumor cells. Inhibits ionizing radiation-induced DNA single-stranded breaks in lymphoid cell lines in vivo.

Technical Data for BSI 201

M. Wt 292.03
Formula C7H5IN2O3
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 160003-66-7
PubChem ID 9796068
Smiles NC(=O)C1=CC=C(I)C(=C1)[N](=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for BSI 201

References are publications that support the biological activity of the product.

Liu et al (2011) Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor. Clin.Cancer Res 18 510 PMID: 22128301

Ma et al (2012) Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus. Proc.Natl.Acad.Sci.U.S.A. 109 6590 PMID: 22493268

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Citations for BSI 201

Citations are publications that use Tocris products.

Currently there are no citations for BSI 201.

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Literature in this Area

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