Ribosomal S6 kinase (RSK) inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in terminally differentiated pancreatic α-cells.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 366.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.73 mL||13.65 mL||27.29 mL|
|5 mM||0.55 mL||2.73 mL||5.46 mL|
|10 mM||0.27 mL||1.36 mL||2.73 mL|
|50 mM||0.05 mL||0.27 mL||0.55 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
If you know of a relevant reference for BRD 7389, please let us know.
View Related Products by Product Action
Keywords: BRD7389 p90 rsk ribosomal s6 kinases inhibitors inhibits rsk1 rsk2 rsk3 RSK
1 Citation for BRD 7389
Citations are publications that use Tocris products. Selected citations for BRD 7389 include:
Breindel et al (2013) EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res 73 5053 PMID: 23794705
Do you know of a great paper that uses BRD 7389 from Tocris? If so please let us know.