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BP 554 maleate
Biological Activity for BP 554 maleate
BP 554 maleate is a selective 5-HT1A agonist.
Technical Data for BP 554 maleate
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for BP 554 maleate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for BP 554 maleate
The following data is based on the product molecular weight 456.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.19 mL||10.95 mL||21.91 mL|
|5 mM||0.44 mL||2.19 mL||4.38 mL|
|10 mM||0.22 mL||1.1 mL||2.19 mL|
|50 mM||0.04 mL||0.22 mL||0.44 mL|
References for BP 554 maleate
References are publications that support the biological activity of the product.
Matsuda et al (1989) Agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (BP-554) at central 5-HT1A receptors. Eur.J.Pharmacol. 170 75 PMID: 2533078
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Keywords: BP 554 maleate, BP 554 maleate supplier, Selective, 5-HT1A, agonists, Serotonin, Receptors, 5-HT1, BP554, maleate, 0556, Tocris Bioscience
2 Citations for BP 554 maleate
Citations are publications that use Tocris products. Selected citations for BP 554 maleate include:
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
Huang et al (2009) Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. Br J Pharmacol 29 13909 PMID: 19890001
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.