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Submit ReviewPotent and selective CB2 receptor ligand (Ki values are 435 nM and > 2 μM for CB2 and CB1 respectively).
M. Wt | 426.9 |
Formula | C23H23ClN2O4 |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 2854-32-2 |
PubChem ID | 2415 |
InChI Key | BJSDNVVWJYDOLK-UHFFFAOYSA-N |
Smiles | COC1=CC=C2N(C(=O)C3=CC=C(Cl)C=C3)C(C)=C(CC(=O)N3CCOCC3)C2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Melck et al (2000) Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. Endocrinology 141 118 PMID: 10614630
Gallant et al (1996) New class of potent ligands for the human peripheral cannabinoid receptor. Bioorg.Med.Chem.Lett. 6 2263
Keywords: BML-190, BML-190 supplier, Potent, selective, CB2, ligands, Cannabinoid, Receptors, cb2r, Indomethacin, morpholinylamide, IMMA, 1383, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for BML-190 include:
Zhang et al (2010) In vitro metabolism of indomet. morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB(2)) in rat liver microsomes. Eur J Pharm Sci 41 163 PMID: 20542112
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