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Description: Bim peptide fragment
Biological Activity for BIM, Biotinylated
BIM, Biotinylated is a bim peptide fragment (residues 81-106) with a biotin moiety attached.
Technical Data for BIM, Biotinylated
| M. Wt | 3637.14 |
| Formula | C161H247N49O44S2 |
| Sequence |
AADMRPEIWIAQELRRIGDEFNAYYARR (Modifications: Ala-1 = (Biotin)-β-Ala, Ala-2 = β-Ala, Arg-28 = C-terminal amide) |
| Storage | Store at -20°C |
| PubChem ID | 90488855 |
| InChI Key | PSNCGLAAPGGYMJ-YLKYZDBHSA-N |
| Smiles | [H]N(CCC(=O)NCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BIM, Biotinylated
References for BIM, Biotinylated
References are publications that support the biological activity of the product.
Whitfield et al (2003) High-throughput methods to detect dimerization of Bcl-2 family proteins. Anal.Biochem. 322 170 PMID: 14596824
Wang et al (2006) Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins. J.Med.Chem. 49 6139 PMID: 17034116
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Keywords: BIM, Biotinylated, BIM, Biotinylated supplier, Bim, peptide, fragment, Bcl-2, Family, 3526, Tocris Bioscience
Citations for BIM, Biotinylated
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Currently there are no citations for BIM, Biotinylated.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.
Programmed Cell Death Poster
There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.
Pathways for BIM, Biotinylated
