Aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 308.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.24 mL||16.21 mL||32.43 mL|
|5 mM||0.65 mL||3.24 mL||6.49 mL|
|10 mM||0.32 mL||1.62 mL||3.24 mL|
|50 mM||0.06 mL||0.32 mL||0.65 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Imamura and Kimura (2000) Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N. Leuk.Lymphoma 37 663 PMID: 11042531
Scornik and Botbol (2001) Bestatin as an experimental tool in mammals. Curr.Drug Metab. 2 67 PMID: 11465152
Umezawa et al (1976) Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J.Antibiot. 29 97 PMID: 931798
If you know of a relevant reference for Bestatin, please let us know.
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Keywords: Bestatin, supplier, Aminopeptidase, inhibitors, inhibits, enkephalin, metabolism, leukotrienes, eicosanoids, A4, hydrolase, Proteases, Proteinases, Ubenimex, Aminopeptidases, Tocris Bioscience
Citations for Bestatin
Citations are publications that use Tocris products.
Currently there are no citations for Bestatin. Do you know of a great paper that uses Bestatin from Tocris? If so please let us know.
Literature in this Area
New Product Guide (Spring/Summer 2017)New
Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
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