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Biological Activity for Bestatin
Bestatin is an aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
Technical Data for Bestatin
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Bestatin
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Bestatin
The following data is based on the product molecular weight 308.38. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||32.43 mL||162.14 mL||324.28 mL|
|0.5 mM||6.49 mL||32.43 mL||64.86 mL|
|1 mM||3.24 mL||16.21 mL||32.43 mL|
|5 mM||0.65 mL||3.24 mL||6.49 mL|
References for Bestatin
References are publications that support the biological activity of the product.
Imamura and Kimura (2000) Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N. Leuk.Lymphoma 37 663 PMID: 11042531
Scornik and Botbol (2001) Bestatin as an experimental tool in mammals. Curr.Drug Metab. 2 67 PMID: 11465152
Umezawa et al (1976) Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J.Antibiot. 29 97 PMID: 931798
If you know of a relevant reference for Bestatin, please let us know.
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Keywords: Bestatin, Bestatin supplier, Aminopeptidase, inhibitors, inhibits, enkephalin, metabolism, leukotrienes, eicosanoids, A4, hydrolase, Proteases, Proteinases, Ubenimex, Aminopeptidases, LTA4, Hydrolase, 1956, Tocris Bioscience
Citations for Bestatin
Citations are publications that use Tocris products.
Currently there are no citations for Bestatin. Do you know of a great paper that uses Bestatin from Tocris? Please let us know.
Reviews for Bestatin
Average Rating: 5 (Based on 1 Review.)
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