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Aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 308.38. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||6.49 mL||32.43 mL||64.86 mL|
|2.5 mM||1.3 mL||6.49 mL||12.97 mL|
|5 mM||0.65 mL||3.24 mL||6.49 mL|
|25 mM||0.13 mL||0.65 mL||1.3 mL|
References are publications that support the biological activity of the product.
Imamura and Kimura (2000) Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N. Leuk.Lymphoma 37 663 PMID: 11042531
Scornik and Botbol (2001) Bestatin as an experimental tool in mammals. Curr.Drug Metab. 2 67 PMID: 11465152
Umezawa et al (1976) Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J.Antibiot. 29 97 PMID: 931798
If you know of a relevant reference for Bestatin, please let us know.
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Keywords: Bestatin, Bestatin supplier, Aminopeptidase, inhibitors, inhibits, enkephalin, metabolism, leukotrienes, eicosanoids, A4, hydrolase, Proteases, Proteinases, Ubenimex, Aminopeptidases, LTA4, Hydrolase, 1956, Tocris Bioscience
Citations for Bestatin
Citations are publications that use Tocris products.
Currently there are no citations for Bestatin. Do you know of a great paper that uses Bestatin from Tocris? Please let us know.
Reviews for Bestatin
Average Rating: 5 (Based on 1 Review.)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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New Product Guide (Fall/Winter 2018/2019)
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
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