Home / Pharmacology / Ion Channels / Ligand-gated Ion Channels / Acetylcholine Nicotinic Receptors / Nicotinic Receptors (Non-selective) / Nicotinic Receptor (Non-selective) Antagonists / Benzoquinonium dibromide

Benzoquinonium dibromide

Cat. No. 0424 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: nAChR antagonist
Chemical Name: N,N'-[(3,6-Dioxo-1,4-cyclohexadiene-1,4-diyl)bis(imino-3,1-propanediyl)]bis[N,N-diethylbenzenemethanaminium]dibromide
Datasheet
Citations
Reviews
Literature (3)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for Benzoquinonium dibromide

Benzoquinonium dibromide is a nicotinic antagonist, ganglion blocker. Activates single channels but blocks open channels at nicotinic receptors.

Technical Data for Benzoquinonium dibromide

M. Wt 706.6
Formula C34H50Br2N4O2
Storage Store at RT
PubChem ID 56972152
InChI Key DVQZHWAYOLXTHE-UHFFFAOYSA-N
Smiles [Br-].[Br-].CC[N+](CC)(CCCNC1=CC(=O)C(NCCC[N+](CC)(CC)CC2=CC=CC=C2)=CC1=O)CC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Benzoquinonium dibromide

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 70.66 100
water 3.53 5 with gentle warming

Preparing Stock Solutions for Benzoquinonium dibromide

The following data is based on the product molecular weight 706.6. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.42 mL 7.08 mL 14.15 mL
5 mM 0.28 mL 1.42 mL 2.83 mL
10 mM 0.14 mL 0.71 mL 1.42 mL
50 mM 0.03 mL 0.14 mL 0.28 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for Benzoquinonium dibromide

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for Benzoquinonium dibromide

References are publications that support the biological activity of the product.

Bowman and Webb (1972) Neuromuscular blocking and ganglia blocking activities of some acetylcholine antagonists in the cat. J.Pharm.Pharmacol. 24 762 PMID: 4403972

Pereira et al (1993) Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. J.Pharmacol.Exp.Ther. 265 1474 PMID: 8510023

If you know of a relevant reference for Benzoquinonium dibromide, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Nicotinic Receptor (Non-selective) Antagonists

Keywords: Benzoquinonium dibromide, Benzoquinonium dibromide supplier, Nicotinic, antagonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, 311-09-1, (Non-selective), 0424, Tocris Bioscience

Citations for Benzoquinonium dibromide

Citations are publications that use Tocris products.

Currently there are no citations for Benzoquinonium dibromide. Do you know of a great paper that uses Benzoquinonium dibromide from Tocris? Please let us know.

Reviews for Benzoquinonium dibromide

There are currently no reviews for this product. Be the first to review Benzoquinonium dibromide and earn rewards!

Have you used Benzoquinonium dibromide?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Pain Research Product Guide

Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Nicotinic ACh Receptors Scientific Review

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.

Pain Poster

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.