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Submit ReviewBAY 677 is an inactive control for BAY 678 (Cat.No.5706).
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY 678 probe summary on the SGC website.
M. Wt | 400.35 |
Formula | C20H15F3N4O2 |
Storage | Store at -20°C |
Purity | ≥98% (HPLC) |
CAS Number | 2117404-84-7 |
PubChem ID | 68944900 |
InChI Key | PGIVGIFOWOVINL-SFHVURJKSA-N |
Smiles | CC(C1=C(N(C2=CC(C(F)(F)F)=CC=C2)C(N[C@H]1C3=CN=C(C#N)C=C3)=O)C)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 40.03 | 100 |
The following data is based on the product molecular weight 400.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.5 mL | 12.49 mL | 24.98 mL |
5 mM | 0.5 mL | 2.5 mL | 5 mL |
10 mM | 0.25 mL | 1.25 mL | 2.5 mL |
50 mM | 0.05 mL | 0.25 mL | 0.5 mL |
References are publications that support the biological activity of the product.
von Nussbaum et al (2015) Freezing the bioactive conformation to boost potency: The identification of BAY 85-8501, a selective and potent inhibitor of human neutrophil elastase for pulmonary diseases. ChemMedChem 10 1163 PMID: 26083237
If you know of a relevant reference for BAY 677, please let us know.
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