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Submit ReviewBAY 677
Description: Inactive control for BAY 678 (Cat.No.5706)
Chemical Name: 5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Purity: ≥98% (HPLC)
Biological Activity for BAY 677
BAY 677 is an inactive control for BAY 678 (Cat.No.5706).
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY 678 probe summary on the SGC website.
Technical Data for BAY 677
| M. Wt | 400.35 |
| Formula | C20H15F3N4O2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 2117404-84-7 |
| PubChem ID | 68944900 |
| InChI Key | PGIVGIFOWOVINL-SFHVURJKSA-N |
| Smiles | CC(C1=C(N(C2=CC(C(F)(F)F)=CC=C2)C(N[C@H]1C3=CN=C(C#N)C=C3)=O)C)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BAY 677
References for BAY 677
References are publications that support the biological activity of the product.
von Nussbaum et al (2015) Freezing the bioactive conformation to boost potency: The identification of BAY 85-8501, a selective and potent inhibitor of human neutrophil elastase for pulmonary diseases. ChemMedChem 10 1163 PMID: 26083237
Keywords: BAY 677, BAY 677 supplier, BAY677, human, neutrophil, elastase, HNE, negative, control, s-enantiomer, Elastase, 6389, Tocris Bioscience
Citations for BAY 677
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Currently there are no citations for BAY 677.
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