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Biological Activity for BAY 6035
BAY 6035 is a potent SMYD3 inhibitor (IC50 = 70 nM for inhibition of MEKK2 methylation in cells). Exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY-6035 probe summary on the SGC website.
Technical Data for BAY 6035
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for BAY 6035
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for BAY 6035
The following data is based on the product molecular weight 396.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.52 mL||12.61 mL||25.22 mL|
|5 mM||0.5 mL||2.52 mL||5.04 mL|
|10 mM||0.25 mL||1.26 mL||2.52 mL|
|50 mM||0.05 mL||0.25 mL||0.5 mL|
References for BAY 6035
References are publications that support the biological activity of the product.
If you know of a relevant reference for BAY 6035, please let us know.
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Keywords: BAY 6035, BAY 6035 supplier, BAY6035, SYMD3, inhibitors, inhibits, histone, lysine, methyltransferase, potent, selective, Other, Lysine, Methyltransferases, 6561, Tocris Bioscience
Citations for BAY 6035
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